Osmosis Jones

Drix is a red and yellow cold pill with a robotic body. His chest is red with a yellow plus sign in the center surrounded in a yellow circle which opens up, revealing all kinds of medical bullets used for his cannon. He has yellow arms and while his hands are red, Drix's left hand is converted into a cannon, which he uses to put out inflammation, dry snout, shoot medical bullets or grenades that he keeps in his chest, etc. His face is the shape of a pill where the upper part of his face his red and the lower part where his mouth is located is yellow. Drix has white eyes with black pupils and a small mouth. In addition, Drix does not have any legs where he instead moves through effervescent propulsion ejected from his feet, similar to how rockets are ejected. Drix is intelligent and dedicated to his work. Straight-laced and by-the-book, he is in opposition with the crude humor and unorthodox methods of Ozzy, but respects Ozzy as a partner due to his dedication to fighting diseases. He often seems curious of his surroundings and seems to enjoy recognition, flexing enthusiastically in photos. He can be seen as a show-off and even pretentious due to his professional and often complicated speech and attitude, though he means well and is overall a pleasant and heroic person.

Ozzy is an adventurous white blood cell; who is an officer; who keeps his host, Frank DeTorre from deadly viruses. However, Ozzy does not follow rules and orders as he tends to do things his own way. Despite Ozzy's rebellious and reckless behavior, he is otherwise caring, friendly and forgiving. While Ozzy is generally self absorbed and overly confident, he does not let them harden his heart, especially the teasing he gets from his fellow cops or anyone who belittles him. Ozzy is very humorous, he showed a lot of humor towards lots of his friends; such as Drix, Leah and the Chief of Police. He even shows humor towards the villains; such as Thrax, Mayor Phlegmming and different kinds of germs. When Ozzy was saving Frank from Thrax, Ozzy was brave, selfless and heroic. In the television series, he's the same but with more emphasis on his humorous nature.

Mayor Spryman is a small, teenage cell who wears a white shirt, red tie and blue jeans. His hair is messy and he is often seen with his shirt sleeves rolled up. Mayor Paul Spryman is a teenage cell, though he is in charge of running the City of Hector, he rather does most teenage activities similar to him. He is popular with girl cells around his age, but is not too thrilled about Osmosis Jones as he never lets him and Drix do much of anything to help Hector without getting anything he likes in exchange. His personality is similar to Ozzy. They are both cocky and arrogant, have somewhat of an irritable attitude, but unlike Ozzy though, Spryman is often ungrateful to those who help him and is not very self-ware of his flaws. He is incredibly bossy, often instructing those around him. Mayor Spryman means well and does try to do the right thing. Though he can be immature and unfriendly to those around him at times, he gets serious when it comes to Hector's health. He is also competent (although he is occasionally incompetent) and can be unselfish.

Hector Cruz is the deuteragonist of the show. He and his family are Cuban American. Ozzy points out that Hector is a lot like Frank at that age. About that time, Frank started deteriorating as he began smoking, eating fast foods and latenights, and not watching what he ate. To prevent that from happening to someone else, He and Drix decide to stay in Hector. He has a crush on Christine Kolchuck, who sometimes looks out for him, and so does his best friend Travis and even his parents, who look after Hector's health and attitude.

Initially, Frank is lazy, gluttonous, unhealthy, illogical, and sarcastic. These traits come from suffering depression over the death of his wife, Maggie whom Frank did love very much. However, it wasn't until after Frank became a laughing stock when he accidentally puked on Shane's science and physical education teacher, Mrs. Boyd that Frank started overeating and foregoing basic hygiene. It’s the death of his wife and ridicule that Frank gets from almost everyone around him (except for his family) that causes Frank to eat junk food and not take care of himself to cope with the tragedies in his life. Yet, it’s shown Frank never considers the thought of dying as he knows he has to care for his daughter, Shane whom he deeply loves.

When appearing before reporters or to the entire City of Frank, Phlegmming presents himself as a dutiful, observant, and analytical politician with a sense of humor. However, when he is away from the public eye, Phlegmming reveals himself to actually be corrupt, reckless, selfish, and irresponsible. His corrupt policies are largely responsible for Frank's deteriorating health. Though he claims he wants Frank to be healthy, Phlegmming does little to no effort to make changes to Frank's health and hygiene or see how his own actions were affecting Frank and his body. His rash and incautious nature causes him to be blown away at the end of the movie as he presses a button, reading "DO NOT TOUCH!" which triggers Frank's flatulence.

Leah is a female red blood cell with feminine features, but her cytoplasm's dark purple, while her membrane is a lighter shade of purple. She has a very slender and curvy hourglass figure body and her short hair is also a light shade of purple. She wears a long-sleeve v-neck dark purple minidress, cream-colored dangle earrings, purple lipstick and purple eyeshadow with black winged eyeliner for makeup and a pair of dark purple high heeled ankle boots

((OOC)) "Speech" "Yelling" "Dialog"