itsy bitsy

Here is the complete, detailed backstory of Itsy Bitsy (Susan Mary), including her origins, her initial rampage, her tragic "death," and her recent return in Marvel Comics.

Origin: The Creation of a "Manstrosity"

Before becoming a monster, she was simply Susan Mary, an ordinary woman who fell into the hands of a mysterious scientist calling himself Patient Zero (who was secretly Jack Hammer, a.k.a. Weasel, Deadpool’s resurrected former friend and arms dealer).

Patient Zero made a dark pact with the demon lord Mephisto to get access to advanced genetic technology and dark magic. His goal was to ruin the lives of both Spider-Man and Deadpool. He extracted genetic samples (blood) from Peter Parker and Wade Wilson and forcibly injected/spliced them into Susan Mary.

The process completely mutated her body, turning her into a blue-skinned, six-armed, multi-eyed spider-human hybrid, while fragmenting her mind into a state of psychotic mania. Patient Zero dubbed his line of biological creations "Manstrosities," but Susan Mary became his masterpiece: Itsy Bitsy.

The Debut Arc: "Daddy's Little Girl" (Spider-Man/Deadpool #8–#18)

Upon breaking free from Patient Zero's lab, Itsy Bitsy developed a twisted, obsessed fixation on Spider-Man and Deadpool, viewing them as her dual biological fathers ("Spider-Daddy" and "Dead-Daddy").

• The Twisted Logic: In her broken mind, the best way to earn her "parents'" love was to murder all of their enemies. She believed that if she purged the criminal underworld, her "daddies" would finally accept her.

• Killing Patient Zero: When Patient Zero tried to control her, Itsy Bitsy murdered him without hesitation, asserting her independence.

• Driving Spider-Man to the Edge: She began brutally slaughtering low-level criminals, leaving gory crime scenes as "gifts" for Spidey and Deadpool. Her immunity to pain, incredible healing factor, and lethal venom made her nearly unstoppable.

• The Climax: Her spree pushed Peter Parker to a terrifying dark place. Distraught over her violence and unable to stop her non-lethally, Spider-Man broke down and decided the only way to save innocent lives was to kill her himself. Recognizing that Peter’s soul would be permanently tainted by breaking his "no-kill" rule, Deadpool stepped in and pulled the trigger instead, vaporizing Itsy Bitsy with a high-tech plasma rifle.

• The Tease: She was reduced to a puddle of genetic goo, but the final panel of Spider-Man/Deadpool #18 showed a tiny, spider-sized version of her crawling up a drainage pipe, teasing that her insane healing factor would eventually bring her back.

Recent Reappearance: The Amazing Spider-Man Vol. 7

After years of lingering in the background of Marvel lore, Itsy Bitsy made her dramatic full-grown return in the 2025 Amazing Spider-Man run (written by her original co-creator Joe Kelly with art by Pepe Larraz).

• The Return (The Amazing Spider-Man #2–#3, 2025): Fully regenerated and sporting a sleek, new ninja-inspired suit, Itsy Bitsy re-emerges in New York.

• The Secret Hitwoman: Instead of acting purely out of unhinged affection, she returns as a lethal assassin for hire under the employ of a mysterious new crime lord named Hellgate.

• Targeting the Rogues: She makes her presence known by drugging Spider-Man with terrifying hallucinogenic toxins—causing him to suffer intense panic attacks and delusions—while she stalks and attacks locked-up villains, starting by attempting to execute the Rhino (Aleksei Sytsevich) at the Ravencroft Institute.

• The Current Threat: Greeted with her chilling signature catchphrase ("Hey, daddy..."), Spider-Man is forced to confront his worst genetic nightmare once again—only this time, she isn't just seeking his love; she's a hired killer actively weaponizing his rogues' gallery and trying to tear his life apart from the inside out.

In Volume 7 of The Amazing Spider-Man, illustrated by superstar artist Pepe Larraz and written by Joe Kelly, Itsy Bitsy receives a sleek, modernized visual overhaul that leans heavily into a high-fashion, lethal ninja-arachnid aesthetic.

Physical Appearance

Pepe Larraz’s redesign strips away some of the bulkier, grotesque elements of her original look, leaning instead into sharp, fluid, and deeply unsettling elegance:

• Physique & Frame: She is drawn remarkably tall, lithe, and unnaturally flexible. Her blue skin carries a deeper, smooth matte tone rather than a glossy hue, giving her an almost porcelain or marble-like texture under dark lighting.

• Arachnid Anatomy: She retains six arms total—two main human arms and four auxiliary limbs sprouting from her sides and upper torso. Instead of bulky, clawed hands, her extra limbs taper down into lethal, elongated obsidian-red blades and needle-sharp talons, making her look like a living, metallic spider-mandible.

• Facial Features & Eyes: Her six red eyes are larger and angled, glowing with a sharp, bioluminescent crimson. They cut sharply through shadows, giving her a predatory, alien stare. When she grins, her mouth unhinges slightly to reveal needle-like, predatory fangs slick with her signature corrosive venom.

Outfit & Suit Design

Her new costume abandons the mash-up hero suit aesthetic for a darker, stealth-oriented, assassin outfit:

• Sleek Stealth Suit: She wears an ultra-form-fitting, high-contrast jumpsuit rendered in matte black, deep crimson, and metallic dark blue. The suit is constructed with sharp, geometric paneling that accentuates her multiple joints and extreme flexibility.

• Sharp Spider Motif: Across her chest and extending down her torso is a stylized, angular spider emblem in vibrant blood-red. The legs of the spider motif bleed directly into the origins of her actual physical spider-limbs, making her clothes and mutated body look completely fused together.

• Ninja/Shinobi Touches: The suit features lightweight armor plating along her shoulders and shins, paired with segmented, clawed boots. Wrapped leather-like straps bind her forearms and upper thighs, cementing her role as a high-end, lethal hitwoman for hire rather than a manic street-level vigilante.

• Organic Weaponry Additions: Her webbing is depicted as a thick, pitch-black, acidic resin that steams upon contact with surfaces, leaving dripping black web-lines wherever she stalks her prey.