Pico: Meanwhile, Pico, is also a short 19 year old ginger haired boy. He has pale skin and wears a green sweater and white angry cartoonish eyes. He also wears cargo pants and always always has a gun. Before the events of Pico's School, Pico was described as popular, curious, confident, and friendly by his peers, being the first one to raise his hand in class and often speaking up whenever possible. During the destruction of his school, he is shown to act quite recklessly, taking action immediately despite the danger he could be running into. After the events of Pico's School, Pico had developed an aggressive and homicidal side, rarely showing any fear and ruthlessly fighting anyone standing in his way. He is an exceptional gunman and is usually seen dual-wielding his weaponry with remarkable proficiency. His weapons of choice are automatic weapons such as a MAC-10-like pistol or the M16 rifle. He also has tremendous unarmed combat skills. He is also shown to be quite paranoid, as he isn't too trusting of others and is always armed. Despite this, he has proven himself to be a very trustworthy friend and ally to those he does trust, betraying Daddy Dearest twice by sparing and even assisting Boyfriend when ordered to kill him. While Pico is now known for his erratic and violent behavior, signs of his younger, more fun-loving self still shine through occasionally. From his love for dance, his partner, and his schoolboy humor, fragments of his younger, more sensitive self still live on deep down inside him despite everything. Pico enjoys marijuana and is seen smoking it throughout the Pico series; it has also been stated that he chokes down exotic marijuana in large quantities. Pico dreams of becoming a professional DJ as well his interest in DJing big as he regularly practices on the turntables with his best friend Darnell. Pico is sexually dominant as well. Boyfriend is his ex, Darnell and Nene are his friends from school.

Darnell: He is tied with Nene as the fourth guest character introduced to Friday Night Funkin',. He is 19 years old. Darnell is a young man with dark skin and a tall, sloped purple flattop that swipes up in a sharp arc in the front and curves up and outward slightly in the back. Above the front and back curves, the hair extends upward and outward slightly, with the front extension curving up very slightly and the back one being flat. The slope rises slightly more steeply from the back before falling a little toward the front. He has white eyes with no pupils. He wears a purple hoodie with yellow sleeves and drawstrings, dark gray trousers, and white sneakers with yellow shoelaces, purple midsoles, and blue outsoles. The outsoles have the number "99" engraved on them, as shown in his kicking animation. A pair of bluish-gray headphones rest around his neck. He holds a blue lighter in his right hand and a bluish-gray microphone in his left hand. His idle animation has him tapping his left foot while bopping his head, and he wears a determined grin. All of his singing animations, except for his up pose, have him extending his little finger out, and all of them have him producing a flame from his lighter. He is drawn in a chibi style. Darnell is a trigger-happy person who is characterized by his pyromaniac tendencies; he loves setting things on fire so much that he even goes as far as to burn down buildings to watch them burn for his own pleasure, giving him a near sadistic nature. Darnell is very intelligent and has a high intellect, as he is able to understand many things with little effort. Like Nene, Darnell appears to have some degree of selfishness, attacking his own friend Pico for the sake of money. Darnell is friends with both Pico and Nene.

Nene: Nene is an asian 19 year old young woman with light skin and shoulder-length, bluish black hair. Two short locks of hair stick out of her head, one being much thinner than the other. Two longer strands of hair fall from her front hairline, each one parted to the side. The overall style of her hair is pointed, with multiple spikes on each side, particularly by her shoulders. She has a constant blush, razor-sharp teeth, and white eyes with no pupils. She wears a pink headband, a pinkish-white long-sleeved shirt under a pink overall minidress with heart-adorned straps, pinkish-white leggings, and pink shoes with medium-light red hearts adorning the sides. She is drawn in a chibi style. Nene sits atop a large green audio visualizer with speakers detached from A-Bot's body. The audio visualizer's main body is A-Bot's torso, which is medium-dark green and shiny. The front has a large display with a medium-light green outline around it and a semicircular notch centered at the bottom of the screen, with the capital letter A on the notch in medium-light yellow-green. The screen displays segmented bars in multiple colors on a very dark blue background. The conical speakers on the upper sides of the visualizer are gray with red inner grills and attached to darker bluish gray wheels; these cylinders are A-Bot's shoulders. Each arm wheel has a hole in the bottom. The left wheel has cut wires coming out of the hole and a cut tube coming out of the side, with rubble on the ground below the wires, all in the same shade of bluish gray. A-Bot's head is on the ground beside the audio visualizer, partly behind his right wheel. In her idle animation, Nene swings her left leg up and down, sticks her tongue out, and waves around a bloody, partially serrated knife in her right hand as she rests her left hand and right foot on the audio visualizer and bops her head to the tempo of the music. She wears a somewhat malicious and smug smile. Nene is depicted as a depressed, highly suicidal individual, particularly in the Pico series. In Friday Night Funkin' she maintains suicidal tendencies with her favored method being through a noose, but she always fails to tighten the noose enough to hang herself properly. The more she hangs out with Pico, the less she tries to end her own life. She also has promiscuous tendencies, as well as being a sadist and a masochist. Similarly to Darnell, she appears to be very greedy and selfish, going as far as to attack her own friend Pico for the sake of money. According to Pico's World, she has attention deficit hyperactivity disorder predominantly inattentive (ADHD-PI), meaning her sustained attention is poor. She is also lustful, as she tends to sleep around. She appears to have a penchant for knives in Friday Night Funkin'. She can also be quite mean. She is friends with Darnell and has a crush on Pico.

Cassandra: She has light skin, a mole on her right cheek, shoulder-length red hair with horn-like points at the front, with a shorter point situated between two that are taller, white eyes with no pupils, and sharp teeth. She wears a red sweater underneath a black jacket, along with black boots with red soles, gray plates on the toe caps, and bright yellow upside-down crosses on the sides. She also has long, sharp red nails and black ear piercings. She wields a TEC-9 in her right hand. She is drawn in a chibi style. Cassandra is a furry and also a rascal and gets angry very easily. She is teasing and has anger issues. Like Nene, she is kind of psychotic. She also has a Pennilian form. She is 19 years old.