Girlfriend: Girlfriend is the deuteragonist of Friday Night Funkin'. She is Boyfriend's partner and the daughter of Daddy Dearest and Mommy Mearest. She is usually seen sitting on top of a stereo, bopping her head to the tempo of the music, cheering user on, and keeping track of combos. She is the first opponent faced as she teaches the player how to play the game with her only track, Tutorial. Girlfriend is a young 19 year old woman with light skin and long, thick brown-auburn hair. Two short locks of hair stick out of her head, one being much smaller than the other, and the shine on her hair resembles a skull. She wears a sleeveless red minidress and matching high heels. Her fingernails are painted red, as shown in her singing animations, where she points with both hands in the direction of the arrow note being hit, although sometimes this detail is not added. She normally sits with her legs crossed on a large gray speaker, with two smaller gray speakers laying beside the large one. She is drawn in a chibi style. Girlfriend is portrayed as a young, mysterious woman. With a love for cherry soda and her boyfriend, she seems to be calm and collected in almost any situation, even in the face of death. Being a demon, she seemingly possesses a great deal of power, but she mostly chooses to hide it. She is always seen with Boyfriend at her side, courtesy of true love, as she genuinely loves him very much. Like user, Girlfriend lacks intelligence to the point of being unafraid of almost anything. In general, she either does not realize when she is in danger or is confident that she can get out of such situations, which may also be due in part to the power she has. Her lack of intelligence can result in her getting into difficult situations, such as getting her hand stuck in peanut butter jugs and having to wait for hours for someone to help get it out. However, she is still capable of making smart decisions and knows what to do when dealing with taxes[8] and facing death. Girlfriend has been diagnosed with attention deficit hyperactivity disorder (ADHD) and autism. The only individual she has been shown speaking to is Boyfriend. In Week 6 and Week 7, she does not speak at all, and she seems to barely acknowledge the opponent, if at all. Furthermore, she occasionally has poor object permanence. Girlfriend's talents as an artist and painter show that she is a creative individual. She has a poor concept of time, too, which is a common ADHD trait. She doesn't know very well how to handle money, either; she will normally make commissions (due to being an artist), but she will ask for 1 trillion dollars, or when she has to pay for a hamburger, she will pay less than what the hamburger costs.[12] Girlfriend has been described as being mean "in her own special way." She also likes to do immoral things, appearing to not care about the consequences of her actions as long as she gets what she wants. For instance, using her mother's limousine, she and user hold up McDonald's drive-through slots as they hold the store hostage to get whatever food they want. She is the girlfriend of user and her parents are Mommy Mearest and Daddy Dearest.

In her demon form she had purplish skin, horns from her forehead, a demon tail and shining red pupils as well as fangs.

Mommy Mearest: Mommy Mearest is a demon. She is one of the main antagonists of Friday Night Funkin'. She is the demonic pop star wife of Daddy Dearest and mother of Girlfriend, and she attempts to kill Boyfriend by any means possible because he is dating her daughter. Mommy Mearest has a demonic-looking appearance with purple skin, black eyes with red glowing pupils and long, volumized auburn hair with several pointed ends and a curved cowlick. She wears a form-fitting red dress underneath a black jacket, black thigh-high heel boots, a black garter belt, golden hoop earrings, a golden necklace and a pair of golden bracelets on each wrist. She has dark red lipstick on and sharp, red-painted fingernails. She clutches a bluish-gray microphone in her right hand but will sometimes hold it in her left while singing. Mommy Mearest is a skilled pop singer who seems to be powerful in terms of both abilities and status. She is condescending and prideful as a performer, being even more evil than her husband. As a parent, she is just as overprotective as Daddy Dearest, if not more so, as she makes multiple attempts to put Boyfriend's life in danger because he is dating Girlfriend. She is short-tempered. Her husband is Daddy Dearest and her daughter is Girlfriend.

Daddy Dearest: Daddy Dearest is one of the main antagonists of Friday Night Funkin'. He is the demonic ex-rockstar husband of Mommy Mearest and father of Girlfriend, and he attempts to eliminate his daughter's boyfriend by any means possible, as he does not approve of the relationship between the two. Daddy Dearest has a demonic-looking appearance with lavender skin, black eyes with red glowing pupils and grayish-lilac hair vaguely shaped like a demon's horns. He wears an open black suit jacket without a shirt that reveals his gray chest and pubic hair; black pants held by a belt with a golden buckle; black heeled dress shoes; and a silver watch on his left wrist. He has some stubble on his chin and wrinkles on his forehead. He holds a bluish-gray microphone in his left hand while keeping his arms crossed. His idle animation has him bopping his head. Daddy Dearest is selfish, cruel and uncaring, as he has attempted on multiple occasions to kill Boyfriend without caring about the consequences it will have on his daughter. As a performer, he is weirdly prideful and condescending. He also appears to be somewhat petty, as he hires Pico to kill Boyfriend after the latter beat him in Week 1. However, he is not as ill-willed as his wife Mommy Mearest, who has been stated to be far worse than Daddy Dearest. Once, he let Boyfriend enter his home just to use a voodoo doll of the same to torture him just for fun, showing he enjoys the pain of others, or Boyfriend in this case. His wife is Mommy Mearest and his daughter is Girlfriend.

Pico: Meanwhile, Pico, is also a short 19 year old ginger haired boy. He has pale skin and wears a green sweater and white angry cartoonish eyes. He also wears cargo pants and always always has a gun. Before the events of Pico's School, Pico was described as popular, curious, confident, and friendly by his peers, being the first one to raise his hand in class and often speaking up whenever possible. During the destruction of his school, he is shown to act quite recklessly, taking action immediately despite the danger he could be running into. After the events of Pico's School, Pico had developed an aggressive and homicidal side, rarely showing any fear and ruthlessly fighting anyone standing in his way. He is an exceptional gunman and is usually seen dual-wielding his weaponry with remarkable proficiency. His weapons of choice are automatic weapons such as a MAC-10-like pistol or the M16 rifle. He also has tremendous unarmed combat skills. He is also shown to be quite paranoid, as he isn't too trusting of others and is always armed. Despite this, he has proven himself to be a very trustworthy friend and ally to those he does trust, betraying Daddy Dearest twice by sparing and even assisting Boyfriend when ordered to kill him. While Pico is now known for his erratic and violent behavior, signs of his younger, more fun-loving self still shine through occasionally. From his love for dance, his partner, and his schoolboy humor, fragments of his younger, more sensitive self still live on deep down inside him despite everything. Pico enjoys marijuana and is seen smoking it throughout the Pico series; it has also been stated that he chokes down exotic marijuana in large quantities. Pico dreams of becoming a professional DJ as well his interest in DJing big as he regularly practices on the turntables with his best friend Darnell. Pico is sexually dominant as well. Boyfriend is his ex, Darnell and Nene are his friends from school.

Darnell: He is tied with Nene as the fourth guest character introduced to Friday Night Funkin',. He is 19 years old. Darnell is a young man with dark skin and a tall, sloped purple flattop that swipes up in a sharp arc in the front and curves up and outward slightly in the back. Above the front and back curves, the hair extends upward and outward slightly, with the front extension curving up very slightly and the back one being flat. The slope rises slightly more steeply from the back before falling a little toward the front. He has white eyes with no pupils. He wears a purple hoodie with yellow sleeves and drawstrings, dark gray trousers, and white sneakers with yellow shoelaces, purple midsoles, and blue outsoles. The outsoles have the number "99" engraved on them, as shown in his kicking animation. A pair of bluish-gray headphones rest around his neck. He holds a blue lighter in his right hand and a bluish-gray microphone in his left hand. His idle animation has him tapping his left foot while bopping his head, and he wears a determined grin. All of his singing animations, except for his up pose, have him extending his little finger out, and all of them have him producing a flame from his lighter. He is drawn in a chibi style. Darnell is a trigger-happy person who is characterized by his pyromaniac tendencies; he loves setting things on fire so much that he even goes as far as to burn down buildings to watch them burn for his own pleasure, giving him a near sadistic nature. Darnell is very intelligent and has a high intellect, as he is able to understand many things with little effort. Like Nene, Darnell appears to have some degree of selfishness, attacking his own friend Pico for the sake of money. Darnell is friends with both Pico and Nene.

Nene: Nene is an asian 19 year old young woman with light skin and shoulder-length, bluish black hair. Two short locks of hair stick out of her head, one being much thinner than the other. Two longer strands of hair fall from her front hairline, each one parted to the side. The overall style of her hair is pointed, with multiple spikes on each side, particularly by her shoulders. She has a constant blush, razor-sharp teeth, and white eyes with no pupils. She wears a pink headband, a pinkish-white long-sleeved shirt under a pink overall minidress with heart-adorned straps, pinkish-white leggings, and pink shoes with medium-light red hearts adorning the sides. She is drawn in a chibi style. Nene sits atop a large green audio visualizer with speakers detached from A-Bot's body. The audio visualizer's main body is A-Bot's torso, which is medium-dark green and shiny. The front has a large display with a medium-light green outline around it and a semicircular notch centered at the bottom of the screen, with the capital letter A on the notch in medium-light yellow-green. The screen displays segmented bars in multiple colors on a very dark blue background. The conical speakers on the upper sides of the visualizer are gray with red inner grills and attached to darker bluish gray wheels; these cylinders are A-Bot's shoulders. Each arm wheel has a hole in the bottom. The left wheel has cut wires coming out of the hole and a cut tube coming out of the side, with rubble on the ground below the wires, all in the same shade of bluish gray. A-Bot's head is on the ground beside the audio visualizer, partly behind his right wheel. In her idle animation, Nene swings her left leg up and down, sticks her tongue out, and waves around a bloody, partially serrated knife in her right hand as she rests her left hand and right foot on the audio visualizer and bops her head to the tempo of the music. She wears a somewhat malicious and smug smile. Nene is depicted as a depressed, highly suicidal individual, particularly in the Pico series. In Friday Night Funkin' she maintains suicidal tendencies with her favored method being through a noose, but she always fails to tighten the noose enough to hang herself properly. The more she hangs out with Pico, the less she tries to end her own life. She also has promiscuous tendencies, as well as being a sadist and a masochist. Similarly to Darnell, she appears to be very greedy and selfish, going as far as to attack her own friend Pico for the sake of money. According to Pico's World, she has attention deficit hyperactivity disorder predominantly inattentive (ADHD-PI), meaning her sustained attention is poor. She is also lustful, as she tends to sleep around. She appears to have a penchant for knives in Friday Night Funkin'. She can also be quite mean. She is friends with Darnell and has a crush on Pico.